Entity Details

Primary name RPC1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14802
EntryNameRPC1_HUMAN
FullNameDNA-directed RNA polymerase III subunit RPC1
TaxID9606
Evidenceevidence at protein level
Length1390
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesPOLR3A

GO terms

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GOName
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0005654 nucleoplasm
GO:0005666 RNA polymerase III complex
GO:0005829 cytosol
GO:0006351 transcription, DNA-templated
GO:0016020 membrane
GO:0032481 positive regulation of type I interferon production
GO:0032728 positive regulation of interferon-beta production
GO:0045087 innate immune response
GO:0046872 metal ion binding
GO:0051607 defense response to virus

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000722 RNA polymerase, alpha subunitDomainDomain
IPR006592 RNA polymerase, N-terminalDomainDomain
IPR007066 RNA polymerase Rpb1, domain 3DomainDomain
IPR007080 RNA polymerase Rpb1, domain 1DomainDomain
IPR007081 RNA polymerase Rpb1, domain 5DomainDomain
IPR007083 RNA polymerase Rpb1, domain 4DomainDomain
IPR035697 DNA-directed RNA polymerase III subunit RPC1, N-terminalDomainDomain
IPR035698 DNA-directed RNA polymerase III subunit RPC1, C-terminalDomainDomain
IPR038120 RNA polymerase Rpb1, funnel domain superfamilyFamilyHomologous superfamily
IPR042102 RNA polymerase Rpb1, domain 3 superfamilyFamilyHomologous superfamily

Diseases

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