Entity Details

Primary name RUFY1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96T51
EntryNameRUFY1_HUMAN
FullNameRUN and FYVE domain-containing protein 1
TaxID9606
Evidenceevidence at protein level
Length708
SequenceStatuscomplete
DateCreated2004-04-13
DateModified2021-06-02

Ontological Relatives

GenesRUFY1

GO terms

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GOName
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005829 cytosol
GO:0006661 phosphatidylinositol biosynthetic process
GO:0006897 endocytosis
GO:0007264 small GTPase mediated signal transduction
GO:0008289 lipid binding
GO:0015031 protein transport
GO:0016607 nuclear speck
GO:0017124 SH3 domain binding
GO:0030100 regulation of endocytosis
GO:0031901 early endosome membrane
GO:0042169 SH2 domain binding
GO:0042802 identical protein binding
GO:0043231 intracellular membrane-bounded organelle
GO:0046872 metal ion binding

Subcellular Location

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Subcellular Location
Cytoplasm
Early endosome membrane

Domains

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DomainNameCategoryType
IPR000306 FYVE zinc fingerDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR004012 RUN domainDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR017455 Zinc finger, FYVE-relatedDomainDomain
IPR037213 RUN domain superfamilyFamilyHomologous superfamily

Diseases

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