Entity Details

Primary name MYOC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99972
EntryNameMYOC_HUMAN
FullNameMyocilin
TaxID9606
Evidenceevidence at protein level
Length504
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesMYOC

GO terms

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GOName
GO:0001649 osteoblast differentiation
GO:0001953 negative regulation of cell-matrix adhesion
GO:0001968 fibronectin binding
GO:0005109 frizzled binding
GO:0005615 extracellular space
GO:0005741 mitochondrial outer membrane
GO:0005743 mitochondrial inner membrane
GO:0005758 mitochondrial intermembrane space
GO:0005783 endoplasmic reticulum
GO:0005791 rough endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005929 cilium
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0014734 skeletal muscle hypertrophy
GO:0022011 myelination in peripheral nervous system
GO:0030335 positive regulation of cell migration
GO:0030971 receptor tyrosine kinase binding
GO:0031175 neuron projection development
GO:0031410 cytoplasmic vesicle
GO:0032027 myosin light chain binding
GO:0033268 node of Ranvier
GO:0035024 negative regulation of Rho protein signal transduction
GO:0038031 non-canonical Wnt signaling pathway via JNK cascade
GO:0038133 ERBB2-ERBB3 signaling pathway
GO:0043408 regulation of MAPK cascade
GO:0045162 clustering of voltage-gated sodium channels
GO:0046872 metal ion binding
GO:0051496 positive regulation of stress fiber assembly
GO:0051497 negative regulation of stress fiber assembly
GO:0051894 positive regulation of focal adhesion assembly
GO:0051897 positive regulation of protein kinase B signaling
GO:0051901 positive regulation of mitochondrial depolarization
GO:0060348 bone development
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasmic vesicle
Endoplasmic reticulum
Golgi apparatus
Mitochondrion
Mitochondrion inner membrane
Mitochondrion intermembrane space
Mitochondrion outer membrane
Rough endoplasmic reticulum
Secreted

Domains

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DomainNameCategoryType
IPR003112 Olfactomedin-like domainDomainDomain
IPR031213 MyocilinFamilyFamily

Diseases

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Interactions

47 interactions

InteractorPartnerSourcesPublicationsLink
MYOC_HUMANSPRC_HUMANIntAct20926826 details
MYOC_HUMANSPRL1_HUMANIntAct20926826 details
MYOC_HUMANSGTA_HUMANBioGRID, IntAct32296183 details
MYOC_HUMANMLRV_HUMANHPRD, UniProt11773029 details
MYOC_HUMANMYOC_HUMANBioGRID, HPRD, UniProt11527946 11773029 16289162 details
MYOC_HUMANNOE3_HUMANBioGRID, HPRD12019210 details
MYOC_HUMANFBN1_HUMANBioGRID, HPRD11923248 details
MYOC_HUMANFINC_HUMANBioGRID, HPRD11773026 details
MYOC_HUMANPEDF_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANACTA_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANG3P_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANFRIL_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANACTB_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANACTG_HUMANBioGRID16289162 details
MYOC_HUMANCLIC1_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANCO1A2_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANCO3A1_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANA2MG_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANLAMA5_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANITA7_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANTIMP1_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANTGFR1_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANTNR1A_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANEF1A1_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANGLO2_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANFUBP1_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANLEG3_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANNOTC2_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANOLFL3_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANCD81_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANRFC1_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANKCRM_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANIGLL1_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANMAEA_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANECE1_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANC1QB_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANKPYM_HUMANBioGRID16289162 details
MYOC_HUMANTKT_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANCAP1_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANENOA_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANALDOA_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANANXA2_HUMANBioGRID, HPRD16289162 details
MYOC_HUMANKPYR_HUMANHPRD16289162 details
MYOC_HUMANVIME_HUMANBioGRID16289162 details
MYOC_HUMANMYH11_HUMANBioGRID16289162 details
MYOC_HUMANTPM1_HUMANBioGRID16289162 details
MYOC_HUMANHSP74_HUMANBioGRID16289162 details