Entity Details

Primary name NGN2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H2A3
EntryNameNGN2_HUMAN
FullNameNeurogenin-2
TaxID9606
Evidenceevidence at protein level
Length272
SequenceStatuscomplete
DateCreated2002-03-27
DateModified2021-06-02

Ontological Relatives

GenesNEUROG2

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0030182 neuron differentiation
GO:0046983 protein dimerization activity
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0070888 E-box binding
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR032655 Neurogenin-2FamilyFamily
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
NGN2_HUMANPFD5_HUMANBioGRID, IntAct32296183 details
NGN2_HUMANASCL1_HUMANHPRD8948587 details
NGN2_HUMANSMCA4_HUMANBioGRID16024661 details