Entity Details

Primary name NRDC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43847
EntryNameNRDC_HUMAN
FullNameNardilysin
TaxID9606
Evidenceevidence at protein level
Length1151
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesNRDC

GO terms

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GOName
GO:0004222 metalloendopeptidase activity
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0009986 cell surface
GO:0046872 metal ion binding
GO:0048408 epidermal growth factor binding
GO:0051044 positive regulation of membrane protein ectodomain proteolysis
GO:0052548 regulation of endopeptidase activity
GO:0120163 negative regulation of cold-induced thermogenesis

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001431 Peptidase M16, zinc-binding siteSiteBinding site
IPR007863 Peptidase M16, C-terminalDomainDomain
IPR011249 Metalloenzyme, LuxS/M16 peptidase-likeFamilyHomologous superfamily
IPR011765 Peptidase M16, N-terminalDomainDomain
IPR032632 Peptidase M16, middle/third domainDomainDomain

Diseases

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