Entity Details

Primary name AGM1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95394
EntryNameAGM1_HUMAN
FullNamePhosphoacetylglucosamine mutase
TaxID9606
Evidenceevidence at protein level
Length542
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesPGM3

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0004610 phosphoacetylglucosamine mutase activity
GO:0004614 phosphoglucomutase activity
GO:0005829 cytosol
GO:0005975 carbohydrate metabolic process
GO:0006041 glucosamine metabolic process
GO:0006048 UDP-N-acetylglucosamine biosynthetic process
GO:0006487 protein N-linked glycosylation
GO:0006493 protein O-linked glycosylation
GO:0007283 spermatogenesis
GO:0019255 glucose 1-phosphate metabolic process
GO:0030097 hemopoiesis

Subcellular Location

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Domains

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DomainNameCategoryType
IPR005843 Alpha-D-phosphohexomutase, C-terminalDomainDomain
IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain IDomainDomain
IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/IIIFamilyHomologous superfamily
IPR016066 Alpha-D-phosphohexomutase, conserved siteSiteConserved site
IPR016657 Phosphoacetylglucosamine mutaseFamilyFamily
IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Disease IDSourceNameDescription
615816 OMIMImmunodeficiency 23 (IMD23)A primary immunodeficiency syndrome characterized by recurrent respiratory and skin infections beginning in early childhood, severe atopy, increased serum IgE, and developmental delay or cognitive impairment of varying severity. The disease is caused by variants affecting the gene represented in this entry.