Entity Details
| Primary name |
HFM1_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | A2PYH4 |
| EntryName | HFM1_HUMAN |
| FullName | Probable ATP-dependent DNA helicase HFM1 |
| TaxID | 9606 |
| Evidence | evidence at transcript level |
| Length | 1435 |
| SequenceStatus | complete |
| DateCreated | 2008-03-18 |
| DateModified | 2021-06-02 |
Subcellular Location
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Domains
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| Domain | Name | Category | Type |
| IPR001650 | Helicase, C-terminal | Domain | Domain |
| IPR004179 | Sec63 domain | Domain | Domain |
| IPR011545 | DEAD/DEAH box helicase domain | Domain | Domain |
| IPR014001 | Helicase superfamily 1/2, ATP-binding domain | Domain | Domain |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase | Family | Homologous superfamily |
| IPR036390 | Winged helix DNA-binding domain superfamily | Family | Homologous superfamily |
Diseases
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| Disease ID | Source | Name | Description |
| 615724 | OMIM | Premature ovarian failure 9 (POF9) | An ovarian disorder defined as the cessation of ovarian function under the age of 40 years. It is characterized by oligomenorrhea or amenorrhea, in the presence of elevated levels of serum gonadotropins and low estradiol. The disease may be caused by variants affecting the gene represented in this entry. |
Interactions
1 interaction