Entity Details

Primary name CNGA1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP29973
EntryNameCNGA1_HUMAN
FullNamecGMP-gated cation channel alpha-1
TaxID9606
Evidenceevidence at protein level
Length690
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesCNGA1

GO terms

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GOName
GO:0005222 intracellular cAMP-activated cation channel activity
GO:0005223 intracellular cGMP-activated cation channel activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007601 visual perception
GO:0016056 rhodopsin mediated signaling pathway
GO:0022400 regulation of rhodopsin mediated signaling pathway
GO:0030553 cGMP binding
GO:0042622 photoreceptor outer segment membrane

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000595 Cyclic nucleotide-binding domainDomainDomain
IPR005821 Ion transport domainDomainDomain
IPR014710 RmlC-like jelly roll foldFamilyHomologous superfamily
IPR018488 Cyclic nucleotide-binding, conserved siteSiteConserved site
IPR018490 Cyclic nucleotide-binding-likeFamilyHomologous superfamily
IPR032406 Cyclic nucleotide-gated channel, C-terminal leucine zipper domainDomainDomain
IPR032945 cGMP-gated cation channel alpha-1FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB04209 DequaliniumDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CNGA1_HUMANNCKX1_HUMANBioGRID, HPRD12693957 details