Entity Details

Primary name GMPR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP36959
EntryNameGMPR1_HUMAN
FullNameGMP reductase 1
TaxID9606
Evidenceevidence at protein level
Length345
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesGMPR

GO terms

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GOName
GO:0003920 GMP reductase activity
GO:0005829 cytosol
GO:0006144 purine nucleobase metabolic process
GO:0006163 purine nucleotide metabolic process
GO:0009409 response to cold
GO:0043101 purine-containing compound salvage
GO:0046872 metal ion binding
GO:1902560 GMP reductase complex

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001093 IMP dehydrogenase/GMP reductaseDomainDomain
IPR005993 GMP reductaseFamilyFamily
IPR013785 Aldolase-type TIM barrelFamilyHomologous superfamily
IPR015875 IMP dehydrogenase / GMP reductase, conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB01972 Guanosine-5'-MonophosphateDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
GMPR1_HUMANGMPR1_HUMANBioGRID, HPRD, IntAct16359702 25416956 details