Entity Details

Primary name DPOE2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP56282
EntryNameDPOE2_HUMAN
FullNameDNA polymerase epsilon subunit 2
TaxID9606
Evidenceevidence at protein level
Length527
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesPOLE2

GO terms

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GOName
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005654 nucleoplasm
GO:0006260 DNA replication
GO:0006261 DNA-dependent DNA replication
GO:0006270 DNA replication initiation
GO:0006281 DNA repair
GO:0008622 epsilon DNA polymerase complex
GO:0016604 nuclear body
GO:0042276 error-prone translesion synthesis
GO:0043231 intracellular membrane-bounded organelle

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR007185 DNA polymerase alpha/delta/epsilon, subunit BDomainDomain
IPR016266 DNA polymerase epsilon, subunit BFamilyFamily
IPR024639 DNA polymerase epsilon subunit B, N-terminalDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00242 CladribineDrugbanksmall molecule