Entity Details

Primary name CTSK
Entity type gene
Source Source Link

Details

PrimaryID1513
RefseqGeneNG_011848
SymbolCTSK
Namecathepsin K
Chromosome1
Location1q21.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCATK_HUMAN

GO terms

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GOName
GO:0000422 autophagy of mitochondrion
GO:0001968 fibronectin binding
GO:0002224 toll-like receptor signaling pathway
GO:0004197 cysteine-type endopeptidase activity
GO:0005518 collagen binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005654 nucleoplasm
GO:0005764 lysosome
GO:0006508 proteolysis
GO:0006590 thyroid hormone generation
GO:0006955 immune response
GO:0008234 cysteine-type peptidase activity
GO:0016324 apical plasma membrane
GO:0022617 extracellular matrix disassembly
GO:0030574 collagen catabolic process
GO:0036021 endolysosome lumen
GO:0043202 lysosomal lumen
GO:0043231 intracellular membrane-bounded organelle
GO:0043394 proteoglycan binding
GO:0045616 regulation of keratinocyte differentiation
GO:0051603 proteolysis involved in cellular protein catabolic process

Diseases

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Disease IDSourceNameDescription
265800 OMIMPycnodysostosis (PKND)A rare autosomal recessive bone disorder characterized by deformity of the skull, maxilla and phalanges, osteosclerosis, and fragility of bone. The disease is caused by variants affecting the gene represented in this entry.

Interactions

12 interactions