Entity Details

Primary name ALAS1
Entity type gene
Source Source Link

Details

PrimaryID211
RefseqGene
SymbolALAS1
Name5'-aminolevulinate synthase 1
Chromosome3
Location3p21.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1989-05-25
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsHEM1_HUMAN

GO terms

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GOName
GO:0001666 response to hypoxia
GO:0003870 5-aminolevulinate synthase activity
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0006782 protoporphyrinogen IX biosynthetic process
GO:0006783 heme biosynthetic process
GO:0007005 mitochondrion organization
GO:0019222 regulation of metabolic process
GO:0030170 pyridoxal phosphate binding
GO:0042541 hemoglobin biosynthetic process
GO:0042802 identical protein binding
GO:0048821 erythrocyte development

Diseases

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Interactions

126 interactions

InteractorPartnerSourcesPublicationsLink
ALAS1EP400BioGRID, IntAct, MINT21516116 25416956 32296183 details
ALAS1POLDIP2BioGRID, IntAct, MINT21516116 25416956 details
ALAS1DUSP19BioGRID, IntAct, MINT21516116 25416956 26186194 28514442 32296183 details
ALAS1PLAUBioGRID, IntAct21988832 details
ALAS1C8orf33BioGRID, MINT21900206 details
ALAS1CDK5BioGRID, MINT21900206 details
ALAS1CDKN1ABioGRID, MINT21900206 details
ALAS1NUDT3BioGRID, MINT21900206 details
ALAS1PIK3CBBioGRID, MINT21900206 details
ALAS1RAP1BBioGRID, MINT21900206 details
ALAS1SUMO2BioGRID, MINT21900206 details
ALAS1TK1BioGRID, MINT21900206 details
ALAS1WIPF1BioGRID, IntAct25416956 details
ALAS1PPLBioGRID, IntAct25416956 32296183 details
ALAS1TMSB10BioGRID, IntAct21516116 25416956 32296183 details
ALAS1TCEA2BioGRID, IntAct25416956 details
ALAS1RTL8BBioGRID, IntAct25416956 32296183 details
ALAS1LONRF1BioGRID, IntAct25416956 32296183 details
ALAS1BCL7ABioGRID, IntAct25416956 details
ALAS1TTC23BioGRID, IntAct25416956 details
ALAS1CDC73BioGRID, IntAct25416956 25910212 31515488 details
ALAS1MTFR2BioGRID, IntAct25416956 details
ALAS1KLHL35BioGRID, IntAct25416956 32814053 details
ALAS1SNX20BioGRID, IntAct25416956 details
ALAS1ZNF564BioGRID, IntAct25416956 32296183 details
ALAS1CERKBioGRID, IntAct25416956 details
ALAS1CCHCR1BioGRID, IntAct25416956 details
ALAS1TEKT4BioGRID, IntAct25416956 32296183 details
ALAS1ZFYVE26BioGRID, IntAct25416956 details
ALAS1SH2D4ABioGRID, IntAct25416956 details
ALAS1GNL3LBioGRID, IntAct25416956 details
ALAS1C2orf42BioGRID, IntAct25416956 details
ALAS1USP20BioGRID, IntAct25416956 details
ALAS1ZNF175BioGRID, IntAct25416956 32296183 details
ALAS1ALAS1BioGRID, IntAct25416956 32296183 details
ALAS1STAMBPBioGRID, HPRD, IntAct16730941 details
ALAS1HSBP1L1BioGRID, IntAct32296183 details
ALAS1KIF9BioGRID, IntAct32296183 details
ALAS1SNRPB2BioGRID, IntAct32296183 details
ALAS1CAP2BioGRID, IntAct32296183 details
ALAS1LRRC45BioGRID, IntAct32296183 details
ALAS1GRXCR1BioGRID, IntAct32296183 details
ALAS1JRKBioGRID, IntAct32296183 details
ALAS1COBLBioGRID, IntAct32296183 details
ALAS1FBXL8BioGRID, IntAct32296183 details
ALAS1RNF168BioGRID, IntAct32296183 details
ALAS1MTSS2BioGRID, IntAct32296183 details
ALAS1UTP14CBioGRID, IntAct32296183 details
ALAS1OXTRBioGRID, MINT28298427 details
ALAS1ICAM5IntAct32814053 details
ALAS1DNALI1IntAct32814053 details
ALAS1TMSB4XBioGRID25416956 details
ALAS1ZMAT1BioGRID25416956 32296183 details
ALAS1PIBF1BioGRID32296183 details
ALAS1FXR1MINT21653829 details
ALAS1VHLBioGRID16234850 details
ALAS1SIRT4IntAct25525879 details
ALAS1CLPPBioGRID, IntAct26058080 details
ALAS1HSCBBioGRID, IntAct28380382 33957083 details
ALAS1OXLD1BioGRID, IntAct26186194 28514442 details
ALAS1TMOD4BioGRID, IntAct28514442 details
ALAS1ECHDC2BioGRID, IntAct28514442 details
ALAS1TRMT61BBioGRID, IntAct28514442 29568061 details
ALAS1NDUFS6BioGRID, IntAct28514442 details
ALAS1TMOD3BioGRID, IntAct28514442 details
ALAS1CAMK2DBioGRID, IntAct28514442 details
ALAS1THEM4BioGRID, IntAct28514442 details
ALAS1FDPSBioGRID, IntAct28514442 details
ALAS1PCK2BioGRID, IntAct28514442 details
ALAS1RCHY1BioGRID, IntAct28514442 details
ALAS1MCATBioGRID, IntAct28514442 details
ALAS1HSPD1BioGRID, IntAct29568061 details
ALAS1MGST3IntAct29568061 details
ALAS1PDK1BioGRID, IntAct29568061 details
ALAS1HMGCLBioGRID26186194 28514442 details
ALAS1MRM1BioGRID29568061 details
ALAS1AGKBioGRID28712724 details
ALAS1KIF14BioGRID31586073 details
ALAS1ACAD9BioGRID32877691 details
ALAS1AUHBioGRID32877691 details
ALAS1MTRFRBioGRID32877691 details
ALAS1C1QBPBioGRID32877691 details
ALAS1GATD3BioGRID32877691 details
ALAS1MTRES1BioGRID32877691 details
ALAS1CCDC90BBioGRID32877691 details
ALAS1CHCHD1BioGRID32877691 details
ALAS1CSBioGRID32877691 34079125 details
ALAS1FASTKD2BioGRID32877691 details
ALAS1FASTKD5BioGRID32877691 details
ALAS1GFM1BioGRID32877691 details
ALAS1GFM2BioGRID32877691 details
ALAS1GRSF1BioGRID32877691 details
ALAS1HINT2BioGRID32877691 details
ALAS1MRPL58BioGRID32877691 details
ALAS1LONP1BioGRID32877691 details
ALAS1LRPPRCBioGRID32877691 details
ALAS1MDH2BioGRID32877691 details
ALAS1METTL17BioGRID32877691 details
ALAS1MRPL11BioGRID32877691 details
ALAS1MRPS26BioGRID32877691 details
ALAS1MTERF3BioGRID32877691 details
ALAS1MTG2BioGRID32877691 details
ALAS1MTIF2BioGRID32877691 details
ALAS1MTIF3BioGRID32877691 details
ALAS1MTRF1BioGRID32877691 details
ALAS1MTRF1LBioGRID32877691 details
ALAS1PMPCABioGRID32877691 details
ALAS1PMPCBBioGRID32877691 details
ALAS1RPUSD4BioGRID32877691 details
ALAS1SLIRPBioGRID32877691 details
ALAS1SSBP1BioGRID32877691 details
ALAS1TACO1BioGRID32877691 details
ALAS1TBRG4BioGRID32877691 details
ALAS1TFAMBioGRID32877691 details
ALAS1TRUB2BioGRID32877691 details
ALAS1TSFMBioGRID32877691 details
ALAS1TUFMBioGRID32877691 details
ALAS1VWA8BioGRID32877691 details
ALAS1RCC1LBioGRID32877691 details
ALAS1EXD2BioGRID32877691 details
ALAS1AARS2BioGRID34079125 details
ALAS1COX8ABioGRID34079125 details
ALAS1PDHA1BioGRID34079125 details
ALAS1TRAP1BioGRID34079125 details
ALAS1MOV10BioGRID22658674 details
ALAS1NXF1BioGRID22658674 details