Entity Details

Primary name ANK2
Entity type gene
Source Source Link

Details

PrimaryID287
RefseqGeneNG_009006
SymbolANK2
Nameankyrin 2
Chromosome4
Location4q25-q26
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-11-22
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsANK2_HUMAN

GO terms

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GOName
GO:0002027 regulation of heart rate
GO:0003283 atrial septum development
GO:0005739 mitochondrion
GO:0005764 lysosome
GO:0005769 early endosome
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0006874 cellular calcium ion homeostasis
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0006897 endocytosis
GO:0008093 cytoskeletal anchor activity
GO:0010628 positive regulation of gene expression
GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling
GO:0014704 intercalated disc
GO:0015031 protein transport
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030018 Z disc
GO:0030315 T-tubule
GO:0030507 spectrin binding
GO:0030674 protein-macromolecule adaptor activity
GO:0031430 M band
GO:0031647 regulation of protein stability
GO:0031672 A band
GO:0033292 T-tubule organization
GO:0033365 protein localization to organelle
GO:0034394 protein localization to cell surface
GO:0034613 cellular protein localization
GO:0036309 protein localization to M-band
GO:0036371 protein localization to T-tubule
GO:0042383 sarcolemma
GO:0043005 neuron projection
GO:0043034 costamere
GO:0043268 positive regulation of potassium ion transport
GO:0044325 transmembrane transporter binding
GO:0045211 postsynaptic membrane
GO:0050821 protein stabilization
GO:0051117 ATPase binding
GO:0051279 regulation of release of sequestered calcium ion into cytosol
GO:0051924 regulation of calcium ion transport
GO:0051928 positive regulation of calcium ion transport
GO:0055037 recycling endosome
GO:0055117 regulation of cardiac muscle contraction
GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization
GO:0070296 sarcoplasmic reticulum calcium ion transport
GO:0070972 protein localization to endoplasmic reticulum
GO:0072659 protein localization to plasma membrane
GO:0086004 regulation of cardiac muscle cell contraction
GO:0086005 ventricular cardiac muscle cell action potential
GO:0086014 atrial cardiac muscle cell action potential
GO:0086015 SA node cell action potential
GO:0086046 membrane depolarization during SA node cell action potential
GO:0086066 atrial cardiac muscle cell to AV node cell communication
GO:0086070 SA node cell to atrial cardiac muscle cell communication
GO:0086091 regulation of heart rate by cardiac conduction
GO:0098907 regulation of SA node cell action potential
GO:0098910 regulation of atrial cardiac muscle cell action potential
GO:0140031 phosphorylation-dependent protein binding
GO:1901018 positive regulation of potassium ion transmembrane transporter activity
GO:1901019 regulation of calcium ion transmembrane transporter activity
GO:1901021 positive regulation of calcium ion transmembrane transporter activity
GO:2001259 positive regulation of cation channel activity

Diseases

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Interactions

67 interactions

InteractorPartnerSourcesPublicationsLink
ANK2TNIKBioGRID, IntAct17043677 31413325 details
ANK2GRB2IntAct17474147 details
ANK2NCK1IntAct17474147 details
ANK2TP53BioGRID, IntAct20195357 details
ANK2TAF9BioGRID, IntAct20195357 details
ANK2GABARAPL1BioGRID, IntAct20562859 29867141 details
ANK2GABARAPL2BioGRID, IntAct20562859 29867141 details
ANK2ANKRD28BioGRID, IntAct23414517 details
ANK2DNAJB5BioGRID, IntAct23414517 details
ANK2EHD3UniProt20489164 details
ANK2SLC8A1DIP16292983 details
ANK2KCNJ11DIP19805355 details
ANK2NDEL1BioGRID, IntAct17043677 31413325 details
ANK2EPB42BioGRID2968981 details
ANK2GABARAPBioGRID29867141 details
ANK2MAP1LC3ABioGRID29867141 details
ANK2MAP1LC3BBioGRID29867141 details
ANK2MAP1LC3CBioGRID29867141 details
ANK2SPTBN1HPRD15262991 details
ANK2OBSCNHPRD, UniProt12527750 details
ANK2DMDIntAct19109891 details
ANK2DCTN4IntAct19109891 details
ANK2MTERF1IntAct20195357 details
ANK2EHD1UniProt20489164 details
ANK2EHD2UniProt20489164 details
ANK2EHD4UniProt20489164 details
ANK2PICALMIntAct31413325 details
ANK2CTNNB1BioGRID, MINT31264976 34079125 details
ANK2SIGMAR1BioGRID, HPRD11149946 details
ANK2ABCE1BioGRID25659154 details
ANK2DNAJB1BioGRID, HPRD15075330 33957083 details
ANK2L1CAMHPRD9832558 details
ANK2NRCAMHPRD11449000 details
ANK2CEP120BioGRID, IntAct26638075 details
ANK2NUFIP1BioGRID, IntAct26186194 28514442 details
ANK2DGUOKBioGRID, IntAct26186194 28514442 details
ANK2HAX1BioGRID, IntAct26186194 28514442 details
ANK2DNAAF2BioGRID, IntAct26186194 28514442 details
ANK2PALM2AKAP2BioGRID, IntAct26186194 28514442 details
ANK2RAPGEF5BioGRID, IntAct28514442 details
ANK2CHL1BioGRID, IntAct28514442 details
ANK2HIF1ANBioGRID, IntAct26972000 28514442 details
ANK2MAPK8IP1BioGRID, IntAct28514442 details
ANK2ABCC8DIP19805355 details
ANK2EZRBioGRID, IntAct29568061 details
ANK2MDC1UniProt29656893 details
ANK2RRBP1BioGRID, IntAct30021884 details
ANK2H1-2BioGRID, IntAct30021884 details
ANK2PRNPBioGRID, UniProt29791485 details
ANK2UBAC2BioGRID, IntAct22119785 details
ANK2MYO1DBioGRID, MINT26949739 details
ANK2FARP1BioGRID, MINT26949739 details
ANK2CRNKL1BioGRID, MINT26949739 details
ANK2FTSJ3BioGRID, MINT26949739 details
ANK2ACOT7BioGRID, MINT26949739 details
ANK2CCT2BioGRID, MINT26949739 details
ANK2POPDC2BioGRID26186194 details
ANK2NTRK1BioGRID25921289 details
ANK2KRASBioGRID30639242 details
ANK2KIF20ABioGRID31586073 details
ANK2DNAJB4BioGRID33957083 details
ANK2FLOT1BioGRID34079125 details
ANK2LYNBioGRID34079125 details
ANK2MARCKSBioGRID34079125 details
ANK2OCLNBioGRID34079125 details
ANK2PFN1BioGRID34079125 details
ANK2ZYXBioGRID34079125 details