Entity Details

Primary name MNX1
Entity type gene
Source Source Link

Details

PrimaryID3110
RefseqGeneNG_013212
SymbolMNX1
Namemotor neuron and pancreas homeobox 1
Chromosome7
Location7q36.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-17
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsMNX1_HUMAN

GO terms

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GOName
GO:0000785 chromatin
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0007417 central nervous system development
GO:0021520 spinal cord motor neuron cell fate specification
GO:0031018 endocrine pancreas development
GO:0048812 neuron projection morphogenesis
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

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Disease IDSourceNameDescription
176450 OMIMCurrarino syndrome (CURRAS)The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. The syndrome occurs in the majority of patients as an autosomal dominant trait. The disease is caused by variants affecting the gene represented in this entry.

Interactions

7 interactions

InteractorPartnerSourcesPublicationsLink
MNX1COPS5BioGRID, IntAct21145461 details
MNX1SEC22BBioGRID, IntAct30021884 details
MNX1RRBP1BioGRID, IntAct30021884 details
MNX1XRCC6BioGRID30585729 details
MNX1COILBioGRID34079125 details
MNX1TRIM25BioGRID29117863 details
MNX1TNIP2BioGRID27609421 details