Entity Details

Primary name MRCKA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ5VT25
EntryNameMRCKA_HUMAN
FullNameSerine/threonine-protein kinase MRCK alpha
TaxID9606
Evidenceevidence at protein level
Length1732
SequenceStatuscomplete
DateCreated2005-11-08
DateModified2021-06-02

Ontological Relatives

GenesCDC42BPA

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005911 cell-cell junction
GO:0006468 protein phosphorylation
GO:0016477 cell migration
GO:0018107 peptidyl-threonine phosphorylation
GO:0030027 lamellipodium
GO:0031032 actomyosin structure organization
GO:0031252 cell leading edge
GO:0031532 actin cytoskeleton reorganization
GO:0035556 intracellular signal transduction
GO:0042641 actomyosin
GO:0042802 identical protein binding
GO:0070062 extracellular exosome
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR000095 CRIB domainDomainDomain
IPR000719 Protein kinase domainDomainDomain
IPR000961 AGC-kinase, C-terminalDomainDomain
IPR001180 Citron homology (CNH) domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR014930 Myotonic dystrophy protein kinase, coiled coilDomainDomain
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR017892 Protein kinase, C-terminalDomainDomain
IPR026611 Serine/threonine-protein kinase MRCK alphaFamilyFamily
IPR031597 KELK-motif containing domainDomainDomain

Diseases

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