Entity Details

Primary name KCNK2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95069
EntryNameKCNK2_HUMAN
FullNamePotassium channel subfamily K member 2
TaxID9606
Evidenceevidence at protein level
Length426
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesKCNK2

GO terms

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GOName
GO:0003231 cardiac ventricle development
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007613 memory
GO:0008076 voltage-gated potassium channel complex
GO:0009612 response to mechanical stimulus
GO:0009986 cell surface
GO:0010942 positive regulation of cell death
GO:0015271 outward rectifier potassium channel activity
GO:0016324 apical plasma membrane
GO:0019870 potassium channel inhibitor activity
GO:0022841 potassium ion leak channel activity
GO:0030322 stabilization of membrane potential
GO:0043025 neuronal cell body
GO:0044305 calyx of Held
GO:0048678 response to axon injury
GO:0060044 negative regulation of cardiac muscle cell proliferation
GO:0071456 cellular response to hypoxia
GO:0071805 potassium ion transmembrane transport
GO:0090102 cochlea development
GO:0097449 astrocyte projection
GO:1900039 positive regulation of cellular response to hypoxia
GO:2000279 negative regulation of DNA biosynthetic process

Subcellular Location

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Subcellular Location
Cell membrane
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR003280 Two pore domain potassium channelFamilyFamily
IPR003976 Two pore domain potassium channel, TREKFamilyFamily
IPR013099 Potassium channel domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00204 DofetilideDrugbanksmall molecule
DB04855 DronedaroneDrugbanksmall molecule

Interactions

0 interactions

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