Entity Details

Primary name MED26_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95402
EntryNameMED26_HUMAN
FullNameMediator of RNA polymerase II transcription subunit 26
TaxID9606
Evidenceevidence at protein level
Length600
SequenceStatuscomplete
DateCreated2003-02-28
DateModified2021-06-02

Ontological Relatives

GenesMED26

GO terms

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GOName
GO:0003712 transcription coregulator activity
GO:0003713 transcription coactivator activity
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0010628 positive regulation of gene expression
GO:0016592 mediator complex
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter
GO:0070847 core mediator complex

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR003617 Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-typeDomainDomain
IPR017923 Transcription factor IIS, N-terminalDomainDomain
IPR031416 Mediator complex subunit 26, C-terminal domainDomainDomain
IPR031417 Mediator complex subunit 26, middle domainDomainDomain
IPR035441 TFIIS/LEDGF domain superfamilyFamilyHomologous superfamily
IPR042376 Mediator of RNA polymerase II transcription subunit 26FamilyFamily

Diseases

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Interactions

25 interactions

InteractorPartnerSourcesPublicationsLink
MED26_HUMANSRBP1_HUMANBioGRID10235267 11834832 16799563 details
MED26_HUMANAURKA_HUMANBioGRID28218735 details
MED26_HUMANCTDP1_HUMANBioGRID16239144 details
MED26_HUMANMED12_HUMANBioGRID, HPRD, IntAct15175163 21729782 23563140 24981860 details
MED26_HUMANMED19_HUMANBioGRID, IntAct14576168 15175163 21729782 23563140 24981860 26186194 28514442 details
MED26_HUMANMED14_HUMANBioGRID, IntAct15175163 21729782 24981860 9989412 details
MED26_HUMANMED13_HUMANBioGRID, IntAct15175163 21729782 23563140 24981860 details
MED26_HUMANMED28_HUMANBioGRID, IntAct15175163 20133760 21729782 24981860 details
MED26_HUMANMED30_HUMANBioGRID, IntAct, MINT15175163 21729782 24981860 details
MED26_HUMANMED18_HUMANBioGRID, IntAct, MINT15175163 20133760 21729782 24981860 28514442 details
MED26_HUMANMED7_HUMANBioGRID, IntAct, MINT15175163 21729782 24882805 24981860 26186194 28514442 details
MED26_HUMANMED4_HUMANBioGRID, IntAct, MINT15175163 21729782 24882805 24981860 25281560 details
MED26_HUMANMED15_HUMANBioGRID, IntAct14657022 15175163 21729782 24981860 details
MED26_HUMANTRRAP_HUMANBioGRID18418385 details
MED26_HUMANQKI_HUMANBioGRID20133760 details
MED26_HUMANMED25_HUMANBioGRID, IntAct14657022 15175163 21729782 details
MED26_HUMANTAD2A_HUMANBioGRID20508642 details
MED26_HUMANELOA1_HUMANBioGRID21729782 details
MED26_HUMANRET1_HUMANHPRD15175163 details
MED26_HUMANTCEA1_HUMANBioGRID21729782 details
MED26_HUMANEAF1_HUMANBioGRID, IntAct21729782 details
MED26_HUMANUBP7_HUMANBioGRID27934968 details
MED26_HUMANCEBPB_HUMANBioGRID14759369 details
MED26_HUMANZC3HD_HUMANBioGRID20133760 details
MED26_HUMANENL_HUMANBioGRID21729782 details