Entity Details

Primary name ATNG_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP54710
EntryNameATNG_HUMAN
FullNameSodium/potassium-transporting ATPase subunit gamma
TaxID9606
Evidenceevidence at protein level
Length66
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesFXYD2

GO terms

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GOName
GO:0001671 ATPase activator activity
GO:0005886 plasma membrane
GO:0005890 sodium:potassium-exchanging ATPase complex
GO:0017080 sodium channel regulator activity
GO:0030674 protein-macromolecule adaptor activity
GO:0034220 ion transmembrane transport
GO:0036376 sodium ion export across plasma membrane
GO:0055085 transmembrane transport
GO:0070062 extracellular exosome
GO:0099106 ion channel regulator activity
GO:1903408 positive regulation of P-type sodium:potassium-exchanging transporter activity
GO:1903779 regulation of cardiac conduction
GO:1990573 potassium ion import across plasma membrane
GO:2000649 regulation of sodium ion transmembrane transporter activity

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000272 Ion-transport regulator, FXYD motifFamilyFamily

Diseases

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Disease IDSourceNameDescription
154020 OMIMHypomagnesemia 2 (HOMG2)A disorder due to primary renal wasting of magnesium. Plasma levels of other electrolytes are normal. The only abnormality found, in addition to low magnesium levels, is lowered renal excretion of calcium resulting in hypocalciuria. The disease is caused by variants affecting the gene represented in this entry.

Drugs

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DrugNameSourceType
DB00606 CyclothiazideDrugbanksmall molecule
DB09479 Rubidium Rb-82Swissprotsmall molecule
DB11590 ThimerosalDrugbanksmall molecule
DB13620 Potassium gluconateSwissprotsmall molecule

Interactions

4 interactions