Entity Details

Primary name CAD15_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP55291
EntryNameCAD15_HUMAN
FullNameCadherin-15
TaxID9606
Evidenceevidence at protein level
Length814
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCDH15

GO terms

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GOName
GO:0005509 calcium ion binding
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005901 caveola
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0016021 integral component of membrane
GO:0016342 catenin complex
GO:0031594 neuromuscular junction
GO:0034332 adherens junction organization
GO:0045296 cadherin binding
GO:0051149 positive regulation of muscle cell differentiation
GO:0070062 extracellular exosome
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000233 Cadherin, cytoplasmic domainDomainDomain
IPR002126 Cadherin-likeDomainDomain
IPR015919 Cadherin-like superfamilyFamilyHomologous superfamily
IPR020894 Cadherin conserved siteSiteConserved site
IPR027397 Catenin binding domain superfamilyFamilyHomologous superfamily
IPR039808 CadherinFamilyFamily

Diseases

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Disease IDSourceNameDescription
612580 OMIMMental retardation, autosomal dominant 3 (MRD3)A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. The disease is caused by variants affecting the gene represented in this entry.