Entity Details

Primary name AMT
Entity type gene
Source Source Link

Details

PrimaryID275
RefseqGeneNG_015986
SymbolAMT
Nameaminomethyltransferase
Chromosome3
Location3p21.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1997-11-18
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsGCST_HUMAN

GO terms

Show/Hide Table
GOName
GO:0004047 aminomethyltransferase activity
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0006546 glycine catabolic process
GO:0008483 transaminase activity
GO:0019464 glycine decarboxylation via glycine cleavage system

Diseases

Show/Hide Table
Disease IDSourceNameDescription
605899 OMIMNon-ketotic hyperglycinemia (NKH)Autosomal recessive disease characterized by accumulation of a large amount of glycine in body fluid and by severe neurological symptoms. The disease is caused by variants affecting the gene represented in this entry.

Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
AMTPDLIM4BioGRID, IntAct32296183 details
AMTVAC14BioGRID, IntAct32296183 details
AMTHSPA8BioGRID25036637 details
AMTPSMA2BioGRID26344197 details
AMTPNPT1BioGRID31536960 details
AMTDDX58BioGRID32513696 details