Entity Details

Primary name CLDN1
Entity type gene
Source Source Link

Details

PrimaryID9076
RefseqGeneNG_021418
SymbolCLDN1
Nameclaudin 1
Chromosome3
Location3q28
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-01-28
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCLD1_HUMAN

GO terms

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GOName
GO:0001618 virus receptor activity
GO:0005198 structural molecule activity
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005923 bicellular tight junction
GO:0007155 cell adhesion
GO:0007568 aging
GO:0008065 establishment of blood-nerve barrier
GO:0009636 response to toxic substance
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016328 lateral plasma membrane
GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
GO:0030335 positive regulation of cell migration
GO:0032496 response to lipopolysaccharide
GO:0032991 protein-containing complex
GO:0034331 cell junction maintenance
GO:0035633 maintenance of blood-brain barrier
GO:0042538 hyperosmotic salinity response
GO:0042802 identical protein binding
GO:0045216 cell-cell junction organization
GO:0045471 response to ethanol
GO:0051259 protein complex oligomerization
GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing
GO:0061436 establishment of skin barrier
GO:0061772 xenobiotic transport across blood-nerve barrier
GO:0070160 tight junction
GO:0070673 response to interleukin-18
GO:0070830 bicellular tight junction assembly
GO:0071284 cellular response to lead ion
GO:0071346 cellular response to interferon-gamma
GO:0071356 cellular response to tumor necrosis factor
GO:0071548 response to dexamethasone
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0090303 positive regulation of wound healing
GO:0090557 establishment of endothelial intestinal barrier
GO:0097421 liver regeneration
GO:1903348 positive regulation of bicellular tight junction assembly
GO:1903545 cellular response to butyrate

Diseases

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Disease IDSourceNameDescription
607626 OMIMIchthyosis-sclerosing cholangitis neonatal syndrome (NISCH)A rare autosomal recessive complex ichthyosis syndrome characterized by scalp hypotrichosis, scarring alopecia, mild diffuse ichthyosis, sclerosing cholangitis and leukocyte vacuolization. The disease is caused by variants affecting the gene represented in this entry.