Entity Details

Primary name DLEC1
Entity type gene
Source Source Link

Details

PrimaryID9940
RefseqGeneNG_023237
SymbolDLEC1
NameDLEC1 cilia and flagella associated protein
Chromosome3
Location3p22.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-05-07
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsDLEC1_HUMAN

GO terms

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GOName
GO:0002357 defense response to tumor cell
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0008285 negative regulation of cell population proliferation

Diseases

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Disease IDSourceNameDescription
133239 OMIMEsophageal cancer (ESCR)A malignancy of the esophagus. The most common types are esophageal squamous cell carcinoma and adenocarcinoma. Cancer of the esophagus remains a devastating disease because it is usually not detected until it has progressed to an advanced incurable stage. The gene represented in this entry may be involved in disease pathogenesis. DLEC1 silencing due to promoter methylation and aberrant transcription may be implicated in the development of esophageal cancer.
211980 OMIMLung cancer (LNCR)A common malignancy affecting tissues of the lung. The most common form of lung cancer is non-small cell lung cancer (NSCLC) that can be divided into 3 major histologic subtypes: squamous cell carcinoma, adenocarcinoma, and large cell lung cancer. NSCLC is often diagnosed at an advanced stage and has a poor prognosis. The gene represented in this entry may be involved in disease pathogenesis. DLEC1 silencing due to promoter methylation and aberrant transcription are implicated in the development of lung cancer.

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
DLEC1BOD1L1BioGRID, IntAct30021884 details
DLEC1H1-1BioGRID, IntAct30021884 details
DLEC1EIF4BBioGRID29228324 details