Entity Details

Primary name IFIX_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6K0P9
EntryNameIFIX_HUMAN
FullNamePyrin and HIN domain-containing protein 1
TaxID9606
Evidenceevidence at protein level
Length492
SequenceStatuscomplete
DateCreated2008-05-20
DateModified2021-06-02

Ontological Relatives

GenesPYHIN1

GO terms

Show/Hide Table
GOName
GO:0002218 activation of innate immune response
GO:0003690 double-stranded DNA binding
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0007049 cell cycle
GO:0016607 nuclear speck
GO:0031625 ubiquitin protein ligase binding
GO:0031648 protein destabilization
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032991 protein-containing complex
GO:0035457 cellular response to interferon-alpha
GO:0035458 cellular response to interferon-beta
GO:0043388 positive regulation of DNA binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0050821 protein stabilization
GO:1900182 positive regulation of protein localization to nucleus
GO:1902164 positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus
Nucleus speckle

Domains

Show/Hide Table
DomainNameCategoryType
IPR004020 DAPIN domainDomainDomain
IPR004021 HIN-200/IF120xDomainDomain
IPR040205 HIN-200 familyFamilyFamily

Diseases

Show/Hide Table