Entity Details

Primary name ALKB2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6NS38
EntryNameALKB2_HUMAN
FullNameDNA oxidative demethylase ALKBH2
TaxID9606
Evidenceevidence at protein level
Length261
SequenceStatuscomplete
DateCreated2006-05-30
DateModified2021-06-02

Ontological Relatives

GenesALKBH2

GO terms

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GOName
GO:0005654 nucleoplasm
GO:0006307 DNA dealkylation involved in DNA repair
GO:0008198 ferrous iron binding
GO:0035511 oxidative DNA demethylation
GO:0043734 DNA-N1-methyladenine dioxygenase activity
GO:0051747 cytosine C-5 DNA demethylase activity
GO:0070989 oxidative demethylation
GO:0080111 DNA demethylation
GO:0103053 1-ethyladenine demethylase activity

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR005123 Oxoglutarate/iron-dependent dioxygenaseDomainDomain
IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-likeDomainDomain
IPR032852 DNA oxidative demethylase ALKBH2FamilyFamily
IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00126 Ascorbic acidDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ALKB2_HUMANGOGA2_HUMANBioGRID, IntAct32296183 details
ALKB2_HUMANARL3_HUMANBioGRID, IntAct27173435 unassigned1312 details