Entity Details

Primary name ERAP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6P179
EntryNameERAP2_HUMAN
FullNameEndoplasmic reticulum aminopeptidase 2
TaxID9606
Evidenceevidence at protein level
Length960
SequenceStatuscomplete
DateCreated2008-01-15
DateModified2021-06-02

Ontological Relatives

GenesERAP2

GO terms

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GOName
GO:0002250 adaptive immune response
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0004177 aminopeptidase activity
GO:0005737 cytoplasm
GO:0005788 endoplasmic reticulum lumen
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0006508 proteolysis
GO:0007165 signal transduction
GO:0008217 regulation of blood pressure
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0016021 integral component of membrane
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0042277 peptide binding
GO:0043171 peptide catabolic process
GO:0070006 metalloaminopeptidase activity

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolaseFamilyFamily
IPR014782 Peptidase M1, membrane alanine aminopeptidaseDomainDomain
IPR024571 ERAP1-like C-terminal domainDomainDomain
IPR033528 ERAP2 aminopeptidaseFamilyFamily
IPR034016 Aminopeptidase N-typeFamilyFamily
IPR042097 Aminopeptidase N-like , N-terminalFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

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