Entity Details

Primary name U17L2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6R6M4
EntryNameU17L2_HUMAN
FullNameUbiquitin carboxyl-terminal hydrolase 17
TaxID9606
Evidenceevidence at protein level
Length530
SequenceStatuscomplete
DateCreated2008-04-29
DateModified2021-06-02

Ontological Relatives

GenesUSP17L2

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0004197 cysteine-type endopeptidase activity
GO:0004843 thiol-dependent deubiquitinase
GO:0005634 nucleus
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006915 apoptotic process
GO:0007093 mitotic cell cycle checkpoint signaling
GO:0010955 negative regulation of protein processing
GO:0016579 protein deubiquitination
GO:0030334 regulation of cell migration
GO:0031064 negative regulation of histone deacetylation
GO:0034260 negative regulation of GTPase activity
GO:0042127 regulation of cell population proliferation
GO:0042981 regulation of apoptotic process
GO:0043547 positive regulation of GTPase activity
GO:0050691 regulation of defense response to virus by host
GO:0070536 protein K63-linked deubiquitination
GO:0071108 protein K48-linked deubiquitination
GO:0071586 CAAX-box protein processing
GO:0090315 negative regulation of protein targeting to membrane
GO:1900027 regulation of ruffle assembly
GO:1900245 positive regulation of MDA-5 signaling pathway
GO:1900246 positive regulation of RIG-I signaling pathway

Subcellular Location

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Subcellular Location
Endoplasmic reticulum
Nucleus

Domains

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DomainNameCategoryType
IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolaseDomainDomain
IPR018200 Ubiquitin specific protease, conserved siteSiteConserved site
IPR028889 Ubiquitin specific protease domainDomainDomain
IPR038765 Papain-like cysteine peptidase superfamilyFamilyHomologous superfamily

Diseases

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