Entity Details

Primary name PNCB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6XQN6
EntryNamePNCB_HUMAN
FullNameNicotinate phosphoribosyltransferase
TaxID9606
Evidenceevidence at protein level
Length538
SequenceStatuscomplete
DateCreated2008-01-15
DateModified2021-06-02

Ontological Relatives

GenesNAPRT

GO terms

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GOName
GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity
GO:0004516 nicotinate phosphoribosyltransferase activity
GO:0005576 extracellular region
GO:0005829 cytosol
GO:0006979 response to oxidative stress
GO:0034355 NAD salvage
GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway
GO:0035578 azurophil granule lumen
GO:0043312 neutrophil degranulation
GO:0046872 metal ion binding
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR006405 Nicotinate phosphoribosyltransferase pncB-typeFamilyFamily
IPR007229 Nicotinate phosphoribosyltransferase familyFamilyFamily
IPR013785 Aldolase-type TIM barrelFamilyHomologous superfamily
IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminalFamilyHomologous superfamily
IPR040727 Nicotinate phosphoribosyltransferase, N-terminal domainDomainDomain
IPR041619 Nicotinate phosphoribosyltransferase C-terminal domainDomainDomain

Diseases

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Interactions

5 interactions