Entity Details

Primary name SPT6H_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ7KZ85
EntryNameSPT6H_HUMAN
FullNameTranscription elongation factor SPT6
TaxID9606
Evidenceevidence at protein level
Length1726
SequenceStatuscomplete
DateCreated2004-08-31
DateModified2021-06-02

Ontological Relatives

GenesSUPT6H

GO terms

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GOName
GO:0001825 blastocyst formation
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0005654 nucleoplasm
GO:0006366 transcription by RNA polymerase II
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0006397 mRNA processing
GO:0008023 transcription elongation factor complex
GO:0008380 RNA splicing
GO:0010793 regulation of mRNA export from nucleus
GO:0016032 viral process
GO:0031491 nucleosome binding
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter
GO:0034728 nucleosome organization
GO:0035327 transcriptionally active chromatin
GO:0042393 histone binding
GO:0042789 mRNA transcription by RNA polymerase II
GO:0045191 regulation of isotype switching
GO:0050684 regulation of mRNA processing
GO:0051028 mRNA transport
GO:0051147 regulation of muscle cell differentiation
GO:0061086 negative regulation of histone H3-K27 methylation
GO:0070827 chromatin maintenance

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000980 SH2 domainDomainDomain
IPR003029 S1 domainDomainDomain
IPR006641 YqgF/RNase H-like domainDomainDomain
IPR010994 RuvA domain 2-likeFamilyHomologous superfamily
IPR012337 Ribonuclease H-like superfamilyFamilyHomologous superfamily
IPR012340 Nucleic acid-binding, OB-foldFamilyHomologous superfamily
IPR017072 Transcription elongation factor Spt6FamilyFamily
IPR022967 RNA-binding domain, S1DomainDomain
IPR028083 Spt6 acidic, N-terminal domainDomainDomain
IPR028088 Helix-turn-helix DNA-binding domain of Spt6DomainDomain
IPR028231 Transcription elongation factor Spt6, YqgF domainDomainDomain
IPR032706 Transcription elongation factor Spt6, helix-hairpin-helix motifDomainDomain
IPR035018 Spt6, SH2 domain, C terminusDomainDomain
IPR035019 Spt6, SH2 domain, N terminusDomainDomain
IPR035420 Spt6, SH2 domainDomainDomain
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily
IPR041692 HHH domain 9DomainDomain

Diseases

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