Entity Details

Primary name PABP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86U42
EntryNamePABP2_HUMAN
FullNamePolyadenylate-binding protein 2
TaxID9606
Evidenceevidence at protein level
Length306
SequenceStatuscomplete
DateCreated2004-04-13
DateModified2021-06-02

Ontological Relatives

GenesPABPN1

GO terms

Show/Hide Table
GOName
GO:0000165 MAPK cascade
GO:0000398 mRNA splicing, via spliceosome
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006369 termination of RNA polymerase II transcription
GO:0006396 RNA processing
GO:0006936 muscle contraction
GO:0016607 nuclear speck
GO:0016973 poly(A)+ mRNA export from nucleus
GO:0031124 mRNA 3'-end processing
GO:0042405 nuclear inclusion body
GO:0046778 modification by virus of host mRNA processing
GO:0070063 RNA polymerase binding
GO:0071222 cellular response to lipopolysaccharide
GO:1904247 positive regulation of polynucleotide adenylyltransferase activity
GO:1990904 ribonucleoprotein complex

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus
Nucleus speckle

Domains

Show/Hide Table
DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR034911 Polyadenylate-binding protein 2FamilyFamily
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table
Disease IDSourceNameDescription
164300 OMIMOculopharyngeal muscular dystrophy (OPMD)A form of late-onset slowly progressive myopathy characterized by eyelid ptosis, dysphagia and, sometimes by other cranial and limb-muscle involvement. The disease is caused by variants affecting the gene represented in this entry.