Entity Details

Primary name ABCAC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86UK0
EntryNameABCAC_HUMAN
FullNameGlucosylceramide transporter ABCA12
TaxID9606
Evidenceevidence at protein level
Length2595
SequenceStatuscomplete
DateCreated2004-08-16
DateModified2021-06-02

Ontological Relatives

GenesABCA12

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0003336 corneocyte desquamation
GO:0005102 signaling receptor binding
GO:0005319 lipid transporter activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006672 ceramide metabolic process
GO:0006869 lipid transport
GO:0006886 intracellular protein transport
GO:0010875 positive regulation of cholesterol efflux
GO:0016021 integral component of membrane
GO:0019725 cellular homeostasis
GO:0031424 keratinization
GO:0032379 positive regulation of intracellular lipid transport
GO:0032940 secretion by cell
GO:0033700 phospholipid efflux
GO:0034040 ATPase-coupled lipid transmembrane transporter activity
GO:0034191 apolipoprotein A-I receptor binding
GO:0035627 ceramide transport
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0043129 surfactant homeostasis
GO:0043231 intracellular membrane-bounded organelle
GO:0045055 regulated exocytosis
GO:0045616 regulation of keratinocyte differentiation
GO:0048286 lung alveolus development
GO:0055088 lipid homeostasis
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0061436 establishment of skin barrier
GO:0072659 protein localization to plasma membrane
GO:0097209 epidermal lamellar body
GO:0097234 epidermal lamellar body membrane
GO:2000010 positive regulation of protein localization to cell surface

Subcellular Location

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Subcellular Location
Cytoplasmic vesicle
Golgi apparatus membrane

Domains

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DomainNameCategoryType
IPR003439 ABC transporter-like, ATP-binding domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR017871 ABC transporter-like, conserved siteSiteConserved site
IPR026082 ABC transporter AFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR030371 ATP-binding cassette subfamily A member 12FamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ABCAC_HUMANABCA1_HUMANbhf-ucl23931754 details