Entity Details

Primary name WDFY1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IWB7
EntryNameWDFY1_HUMAN
FullNameWD repeat and FYVE domain-containing protein 1
TaxID9606
Evidenceevidence at protein level
Length410
SequenceStatuscomplete
DateCreated2004-08-16
DateModified2021-06-02

Ontological Relatives

GenesWDFY1

GO terms

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GOName
GO:0005545 1-phosphatidylinositol binding
GO:0005634 nucleus
GO:0005769 early endosome
GO:0005829 cytosol
GO:0008270 zinc ion binding
GO:0034141 positive regulation of toll-like receptor 3 signaling pathway
GO:0034145 positive regulation of toll-like receptor 4 signaling pathway

Subcellular Location

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Subcellular Location
Early endosome

Domains

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DomainNameCategoryType
IPR000306 FYVE zinc fingerDomainDomain
IPR001680 WD40 repeatRepeatRepeat
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR017455 Zinc finger, FYVE-relatedDomainDomain
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR020472 G-protein beta WD-40 repeatRepeatRepeat
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily
IPR042234 WD repeat and FYVE domain-containing protein 1/2FamilyFamily
IPR042733 WDFY1, FYVE domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
WDFY1_HUMANTLR3_HUMANBioGRID25736436 details