Entity Details

Primary name MIRO1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IXI2
EntryNameMIRO1_HUMAN
FullNameMitochondrial Rho GTPase 1
TaxID9606
Evidenceevidence at protein level
Length618
SequenceStatuscomplete
DateCreated2006-06-13
DateModified2021-06-02

Ontological Relatives

GenesRHOT1

GO terms

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GOName
GO:0003924 GTPase activity
GO:0005509 calcium ion binding
GO:0005525 GTP binding
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005829 cytosol
GO:0007005 mitochondrion organization
GO:0010821 regulation of mitochondrion organization
GO:0016020 membrane
GO:0016579 protein deubiquitination
GO:0019725 cellular homeostasis
GO:0031307 integral component of mitochondrial outer membrane
GO:0034640 establishment of mitochondrion localization by microtubule attachment
GO:0046928 regulation of neurotransmitter secretion
GO:0047497 mitochondrion transport along microtubule
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0097345 mitochondrial outer membrane permeabilization
GO:1902513 regulation of organelle transport along microtubule

Subcellular Location

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Subcellular Location
Mitochondrion outer membrane

Domains

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DomainNameCategoryType
IPR001806 Small GTPaseFamilyFamily
IPR002048 EF-hand domainDomainDomain
IPR005225 Small GTP-binding protein domainDomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR013566 EF hand associated, type-1DomainDomain
IPR013567 EF hand associated, type-2DomainDomain
IPR018247 EF-Hand 1, calcium-binding siteSiteBinding site
IPR020860 MIRO domainDomainDomain
IPR021181 Mitochondrial Rho GTPaseFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR029506 Mitochondrial Rho GTPase 1FamilyFamily

Diseases

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