Entity Details

Primary name EF2K_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00418
EntryNameEF2K_HUMAN
FullNameEukaryotic elongation factor 2 kinase
TaxID9606
Evidenceevidence at protein level
Length725
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesEEF2K

GO terms

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GOName
GO:0002931 response to ischemia
GO:0004672 protein kinase activity
GO:0004686 elongation factor-2 kinase activity
GO:0005509 calcium ion binding
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006414 translational elongation
GO:0008135 translation factor activity, RNA binding
GO:0014069 postsynaptic density
GO:0031952 regulation of protein autophosphorylation
GO:0032869 cellular response to insulin stimulus
GO:0043066 negative regulation of apoptotic process
GO:0043197 dendritic spine
GO:0045807 positive regulation of endocytosis
GO:0046777 protein autophosphorylation
GO:0051965 positive regulation of synapse assembly
GO:0061003 positive regulation of dendritic spine morphogenesis
GO:0071277 cellular response to calcium ion
GO:0071320 cellular response to cAMP
GO:0071454 cellular response to anoxia
GO:1990416 cellular response to brain-derived neurotrophic factor stimulus
GO:1990637 response to prolactin

Subcellular Location

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Domains

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DomainNameCategoryType
IPR004166 MHCK/EF2 kinaseDomainDomain
IPR006597 Sel1-like repeatRepeatRepeat
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR011990 Tetratricopeptide-like helical domain superfamilyFamilyHomologous superfamily
IPR017400 Eukaryotic elongation factor 2 kinaseFamilyFamily

Diseases

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