Entity Details

Primary name TRPV1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NER1
EntryNameTRPV1_HUMAN
FullNameTransient receptor potential cation channel subfamily V member 1
TaxID9606
Evidenceevidence at protein level
Length839
SequenceStatuscomplete
DateCreated2005-04-26
DateModified2021-06-02

Ontological Relatives

GenesTRPV1

GO terms

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GOName
GO:0004888 transmembrane signaling receptor activity
GO:0005216 ion channel activity
GO:0005230 extracellular ligand-gated ion channel activity
GO:0005231 excitatory extracellular ligand-gated ion channel activity
GO:0005262 calcium channel activity
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007166 cell surface receptor signaling pathway
GO:0007635 chemosensory behavior
GO:0015278 calcium-release channel activity
GO:0016021 integral component of membrane
GO:0031226 intrinsic component of plasma membrane
GO:0032591 dendritic spine membrane
GO:0034605 cellular response to heat
GO:0035091 phosphatidylinositol binding
GO:0045211 postsynaptic membrane
GO:0046872 metal ion binding
GO:0050955 thermoception
GO:0051219 phosphoprotein binding
GO:0051289 protein homotetramerization
GO:0070588 calcium ion transmembrane transport
GO:0071312 cellular response to alkaloid
GO:0071318 cellular response to ATP
GO:0071468 cellular response to acidic pH
GO:0098703 calcium ion import across plasma membrane
GO:1901594 response to capsazepine

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection

Domains

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DomainNameCategoryType
IPR002110 Ankyrin repeatRepeatRepeat
IPR005821 Ion transport domainDomainDomain
IPR008347 Transient receptor potential channel, vanilloid 1-4FamilyFamily
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR024862 Transient receptor potential cation channel subfamily VFamilyFamily
IPR024863 Transient receptor potential cation channel subfamily V member 1FamilyFamily
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00132 alpha-Linolenic acidDrugbanksmall molecule
DB00159 IcosapentDrugbanksmall molecule
DB00168 AspartameDrugbanksmall molecule
DB00193 TramadolDrugbanksmall molecule
DB00316 AcetaminophenDrugbanksmall molecule
DB01744 CamphorDrugbanksmall molecule
DB02955 Ricinoleic AcidDrugbanksmall molecule
DB06515 ResiniferatoxinDrugbanksmall molecule
DB06774 CapsaicinDrugbanksmall molecule
DB09061 CannabidiolDrugbanksmall molecule
DB09120 ZucapsaicinDrugbanksmall molecule
DB09288 PropacetamolDrugbanksmall molecule
DB11131 Capsicum oleoresinDrugbankbiotech
DB11324 NonivamideDrugbanksmall molecule
DB11345 (S)-camphorDrugbanksmall molecule
DB14009 Medical CannabisDrugbankbiotech
DB14011 NabiximolsDrugbanksmall molecule
DB14050 CannabidivarinDrugbanksmall molecule