Entity Details

Primary name TET1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NFU7
EntryNameTET1_HUMAN
FullNameMethylcytosine dioxygenase TET1
TaxID9606
Evidenceevidence at protein level
Length2136
SequenceStatuscomplete
DateCreated2006-10-03
DateModified2021-06-02

Ontological Relatives

GenesTET1

GO terms

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GOName
GO:0001826 inner cell mass cell differentiation
GO:0003677 DNA binding
GO:0005506 iron ion binding
GO:0005634 nucleus
GO:0006211 5-methylcytosine catabolic process
GO:0006325 chromatin organization
GO:0006493 protein O-linked glycosylation
GO:0008270 zinc ion binding
GO:0008284 positive regulation of cell population proliferation
GO:0008327 methyl-CpG binding
GO:0019827 stem cell population maintenance
GO:0031062 positive regulation of histone methylation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0070579 methylcytosine dioxygenase activity
GO:0070989 oxidative demethylation
GO:0080111 DNA demethylation
GO:0090310 negative regulation of DNA methylation-dependent heterochromatin assembly

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR002857 Zinc finger, CXXC-typeDomainDomain
IPR024779 2OGFeDO, oxygenase domainDomainDomain
IPR040175 Methylcytosine dioxygenase TET1/2/3FamilyFamily

Diseases

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