Entity Details

Primary name FCN1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00602
EntryNameFCN1_HUMAN
FullNameFicolin-1
TaxID9606
Evidenceevidence at protein level
Length326
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesFCN1

GO terms

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GOName
GO:0001664 G protein-coupled receptor binding
GO:0001867 complement activation, lectin pathway
GO:0002752 cell surface pattern recognition receptor signaling pathway
GO:0003823 antigen binding
GO:0005102 signaling receptor binding
GO:0005576 extracellular region
GO:0005581 collagen trimer
GO:0005615 extracellular space
GO:0006956 complement activation
GO:0007186 G protein-coupled receptor signaling pathway
GO:0030246 carbohydrate binding
GO:0031232 extrinsic component of external side of plasma membrane
GO:0032757 positive regulation of interleukin-8 production
GO:0033691 sialic acid binding
GO:0034394 protein localization to cell surface
GO:0034774 secretory granule lumen
GO:0038187 pattern recognition receptor activity
GO:0043312 neutrophil degranulation
GO:0043654 recognition of apoptotic cell
GO:0046597 negative regulation of viral entry into host cell
GO:0046872 metal ion binding
GO:0062023 collagen-containing extracellular matrix
GO:0097367 carbohydrate derivative binding
GO:1904813 ficolin-1-rich granule lumen

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domainDomainDomain
IPR008160 Collagen triple helix repeatRepeatRepeat
IPR014716 Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1FamilyHomologous superfamily
IPR020837 Fibrinogen, conserved siteSiteConserved site
IPR036056 Fibrinogen-like, C-terminalFamilyHomologous superfamily

Diseases

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