Entity Details

Primary name MK15_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TD08
EntryNameMK15_HUMAN
FullNameMitogen-activated protein kinase 15
TaxID9606
Evidenceevidence at protein level
Length544
SequenceStatuscomplete
DateCreated2006-04-18
DateModified2021-06-02

Ontological Relatives

GenesMAPK15

GO terms

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GOName
GO:0003400 regulation of COPII vesicle coating
GO:0003682 chromatin binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004707 MAP kinase activity
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005776 autophagosome
GO:0005794 Golgi apparatus
GO:0005814 centriole
GO:0005911 cell-cell junction
GO:0005923 bicellular tight junction
GO:0006974 cellular response to DNA damage stimulus
GO:0007029 endoplasmic reticulum organization
GO:0008284 positive regulation of cell population proliferation
GO:0010506 regulation of autophagy
GO:0016301 kinase activity
GO:0017124 SH3 domain binding
GO:0030336 negative regulation of cell migration
GO:0031410 cytoplasmic vesicle
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0035556 intracellular signal transduction
GO:0036064 ciliary basal body
GO:0046777 protein autophosphorylation
GO:0051973 positive regulation of telomerase activity
GO:0072687 meiotic spindle
GO:0090494 dopamine uptake
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1902017 regulation of cilium assembly
GO:1904355 positive regulation of telomere capping
GO:1904491 protein localization to ciliary transition zone
GO:1905188 positive regulation of metaphase/anaphase transition of meiosis I
GO:1905832 positive regulation of spindle assembly

Subcellular Location

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Subcellular Location
Cell junction
Cytoplasm
Cytoplasmic vesicle
Golgi apparatus
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR003527 Mitogen-activated protein (MAP) kinase, conserved siteSiteConserved site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site

Diseases

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Drugs

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DrugNameSourceType
DB00945 Acetylsalicylic acidDrugbanksmall molecule
DB01017 MinocyclineDrugbanksmall molecule
DB12010 FostamatinibDrugbanksmall molecule