Entity Details

Primary name PYDC1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8WXC3
EntryNamePYDC1_HUMAN
FullNamePyrin domain-containing protein 1
TaxID9606
Evidenceevidence at protein level
Length89
SequenceStatuscomplete
DateCreated2007-03-20
DateModified2021-06-02

Ontological Relatives

GenesPYDC1

GO terms

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GOName
GO:0004197 cysteine-type endopeptidase activity
GO:0005634 nucleus
GO:0005829 cytosol
GO:0006469 negative regulation of protein kinase activity
GO:0008385 IkappaB kinase complex
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032731 positive regulation of interleukin-1 beta production
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0045087 innate immune response

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002398 Peptidase C14 familyFamilyFamily
IPR004020 DAPIN domainDomainDomain
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PYDC1_HUMANASC_HUMANUniProt17178784 details
PYDC1_HUMANWDR82_HUMANBioGRID20516061 details