Entity Details

Primary name PIEZ1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92508
EntryNamePIEZ1_HUMAN
FullNamePiezo-type mechanosensitive ion channel component 1
TaxID9606
Evidenceevidence at protein level
Length2521
SequenceStatuscomplete
DateCreated2001-10-18
DateModified2021-06-02

Ontological Relatives

GenesPIEZO1

GO terms

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GOName
GO:0005261 cation channel activity
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0006812 cation transport
GO:0008381 mechanosensitive ion channel activity
GO:0010831 positive regulation of myotube differentiation
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031258 lamellipodium membrane
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0033625 positive regulation of integrin activation
GO:0033634 positive regulation of cell-cell adhesion mediated by integrin
GO:0042391 regulation of membrane potential
GO:0050982 detection of mechanical stimulus
GO:0071260 cellular response to mechanical stimulus

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Endoplasmic reticulum membrane
Endoplasmic reticulum-Golgi intermediate compartment membrane

Domains

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DomainNameCategoryType
IPR027272 Piezo familyFamilyFamily
IPR031334 Piezo non-specific cation channel, R-Ras-binding domainDomainDomain
IPR031805 Piezo domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PIEZ1_HUMANTFF1_HUMANIntAct24798994 details
PIEZ1_HUMANFBX7_HUMANBioGRID27503909 details