Entity Details

Primary name LPAR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92633
EntryNameLPAR1_HUMAN
FullNameLysophosphatidic acid receptor 1
TaxID9606
Evidenceevidence at protein level
Length364
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesLPAR1

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001965 G-protein alpha-subunit binding
GO:0004930 G protein-coupled receptor activity
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007202 activation of phospholipase C activity
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0008360 regulation of cell shape
GO:0009986 cell surface
GO:0010977 negative regulation of neuron projection development
GO:0014003 oligodendrocyte development
GO:0019222 regulation of metabolic process
GO:0021549 cerebellum development
GO:0021554 optic nerve development
GO:0022008 neurogenesis
GO:0022038 corpus callosum development
GO:0030165 PDZ domain binding
GO:0032060 bleb assembly
GO:0035025 positive regulation of Rho protein signal transduction
GO:0035727 lysophosphatidic acid binding
GO:0042552 myelination
GO:0043025 neuronal cell body
GO:0043065 positive regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043197 dendritic spine
GO:0043198 dendritic shaft
GO:0043410 positive regulation of MAPK cascade
GO:0043951 negative regulation of cAMP-mediated signaling
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
GO:0051496 positive regulation of stress fiber assembly
GO:0060326 cell chemotaxis
GO:0060999 positive regulation of dendritic spine development
GO:0070915 lysophosphatidic acid receptor activity
GO:0071453 cellular response to oxygen levels
GO:0071673 positive regulation of smooth muscle cell chemotaxis
GO:1904566 cellular response to 1-oleoyl-sn-glycerol 3-phosphate

Subcellular Location

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Subcellular Location
Cell membrane
Cell surface
Endosome

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR002277 Lysophosphatidic acid receptor EDG-2FamilyFamily
IPR004065 Lysophosphatidic acid receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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