Entity Details

Primary name STAM1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92783
EntryNameSTAM1_HUMAN
FullNameSignal transducing adapter molecule 1
TaxID9606
Evidenceevidence at protein level
Length540
SequenceStatuscomplete
DateCreated2005-07-19
DateModified2021-06-02

Ontological Relatives

GenesSTAM

GO terms

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GOName
GO:0005829 cytosol
GO:0007165 signal transduction
GO:0016197 endosomal transport
GO:0016236 macroautophagy
GO:0016579 protein deubiquitination
GO:0031901 early endosome membrane
GO:0033565 ESCRT-0 complex
GO:0036258 multivesicular body assembly
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0043231 intracellular membrane-bounded organelle
GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0044389 ubiquitin-like protein ligase binding
GO:0061024 membrane organization
GO:1903543 positive regulation of exosomal secretion
GO:1903551 regulation of extracellular exosome assembly

Subcellular Location

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Subcellular Location
Cytoplasm
Early endosome membrane

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR002014 VHS domainDomainDomain
IPR003903 Ubiquitin interacting motifSiteConserved site
IPR008942 ENTH/VHSFamilyHomologous superfamily
IPR035657 STAM1, SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

45 interactions

InteractorPartnerSourcesPublicationsLink
STAM1_HUMANUBC_HUMANBioGRID, MINT12750381 16771824 17078930 19111546 20150893 20504764 21187078 23035694 23314748 26456826 26601948 28190767 31699778 details
STAM1_HUMANPP1A_HUMANBioGRID, HPRD, MINT15231748 details
STAM1_HUMANHGS_HUMANBioGRID, DIP, HPRD, IntAct12551915 13679051 16189514 19278655 20505072 20736164 22939629 24344129 24790097 26344197 28514442 29604273 29892012 31515488 32296183 9407053 details
STAM1_HUMANSTABP_HUMANBioGRID, HPRD, IntAct, MINT, UniProt10383417 10982817 12810066 15314065 16431367 16520378 16730941 16760479 17078930 20159979 24151880 details
STAM1_HUMANLCP2_HUMANMINT17235283 details
STAM1_HUMANMED28_HUMANBioGRID, MINT16964398 details
STAM1_HUMANASAP1_HUMANMINT16636290 details
STAM1_HUMANCLAT_HUMANIntAct32814053 details
STAM1_HUMANFGFR3_HUMANIntAct32814053 details
STAM1_HUMANRASH_HUMANIntAct32814053 details
STAM1_HUMANLSAMP_HUMANIntAct32814053 details
STAM1_HUMANNUP58_HUMANIntAct32814053 details
STAM1_HUMANRNF11_HUMANIntAct32814053 details
STAM1_HUMANTIM8A_HUMANBioGRID, HPRD12745081 details
STAM1_HUMANUBP8_HUMANBioGRID, HPRD10982817 16520378 20736164 29604273 details
STAM1_HUMANJAK2_HUMANBioGRID, HPRD9133424 details
STAM1_HUMANCLH1_HUMANBioGRID16431367 16716190 29604273 details
STAM1_HUMANARRB1_HUMANBioGRID20505072 details
STAM1_HUMANITCH_HUMANBioGRID22275353 26508657 details
STAM1_HUMANRFFL_HUMANBioGRID22626734 details
STAM1_HUMANPJA1_HUMANBioGRID22626734 details
STAM1_HUMANTRI63_HUMANBioGRID22626734 details
STAM1_HUMANTRI55_HUMANBioGRID22626734 details
STAM1_HUMANTRI54_HUMANBioGRID22626734 details
STAM1_HUMANUBP15_HUMANBioGRID22626734 details
STAM1_HUMANUBP28_HUMANBioGRID22626734 details
STAM1_HUMANPP1G_HUMANBioGRID23080069 details
STAM1_HUMANM3K1_HUMANBioGRID25260751 details
STAM1_HUMANPMEPA_HUMANBioGRID28218281 details
STAM1_HUMANJAK3_HUMANBioGRID, HPRD10899310 9133424 details
STAM1_HUMANCXCR4_HUMANBioGRID20505072 22275353 details
STAM1_HUMANCD79B_HUMANBioGRID17878339 details
STAM1_HUMANSC31A_HUMANBioGRID19054391 29604273 details
STAM1_HUMANSTAM2_HUMANBioGRID13679051 details
STAM1_HUMANSORT_HUMANBioGRID11390366 details
STAM1_HUMANUBE4B_HUMANBioGRID24344129 details
STAM1_HUMANDTX3L_HUMANBioGRID24790097 details
STAM1_HUMANPTN23_HUMANBioGRID26456826 details
STAM1_HUMANARRD3_HUMANBioGRID27226565 details
STAM1_HUMANHAVR1_HUMANBioGRID29742433 details
STAM1_HUMANCLH2_HUMANBioGRID29604273 details
STAM1_HUMANPDC6I_HUMANBioGRID29604273 details
STAM1_HUMANSEC13_HUMANBioGRID29604273 details
STAM1_HUMANSC24B_HUMANBioGRID29604273 details
STAM1_HUMANJAK1_HUMANHPRD9133424 details