Entity Details

Primary name SEM4D_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92854
EntryNameSEM4D_HUMAN
FullNameSemaphorin-4D
TaxID9606
Evidenceevidence at protein level
Length862
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesSEMA4D

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001755 neural crest cell migration
GO:0001934 positive regulation of protein phosphorylation
GO:0004888 transmembrane signaling receptor activity
GO:0005102 signaling receptor binding
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006955 immune response
GO:0007155 cell adhesion
GO:0007162 negative regulation of cell adhesion
GO:0007411 axon guidance
GO:0008360 regulation of cell shape
GO:0010693 negative regulation of alkaline phosphatase activity
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0030215 semaphorin receptor binding
GO:0030335 positive regulation of cell migration
GO:0031344 regulation of cell projection organization
GO:0038023 signaling receptor activity
GO:0042802 identical protein binding
GO:0043066 negative regulation of apoptotic process
GO:0043547 positive regulation of GTPase activity
GO:0043931 ossification involved in bone maturation
GO:0045499 chemorepellent activity
GO:0045668 negative regulation of osteoblast differentiation
GO:0048672 positive regulation of collateral sprouting
GO:0048814 regulation of dendrite morphogenesis
GO:0048843 negative regulation of axon extension involved in axon guidance
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation
GO:0050919 negative chemotaxis
GO:0070486 leukocyte aggregation
GO:0071526 semaphorin-plexin signaling pathway
GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis
GO:1905704 positive regulation of inhibitory synapse assembly

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR001627 Sema domainDomainDomain
IPR002165 Plexin repeatRepeatRepeat
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013151 ImmunoglobulinDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR016201 PSI domainDomainDomain
IPR027231 SemaphorinFamilyFamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR036352 Sema domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

5 interactions