Entity Details

Primary name AZIN2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96A70
EntryNameAZIN2_HUMAN
FullNameAntizyme inhibitor 2
TaxID9606
Evidenceevidence at protein level
Length460
SequenceStatuscomplete
DateCreated2002-11-01
DateModified2021-06-02

Ontological Relatives

GenesAZIN2

GO terms

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GOName
GO:0003824 catalytic activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005801 cis-Golgi network
GO:0005802 trans-Golgi network
GO:0005829 cytosol
GO:0007283 spermatogenesis
GO:0030133 transport vesicle
GO:0030424 axon
GO:0030425 dendrite
GO:0031410 cytoplasmic vesicle
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0033387 putrescine biosynthetic process from ornithine
GO:0042177 negative regulation of protein catabolic process
GO:0042978 ornithine decarboxylase activator activity
GO:0043085 positive regulation of catalytic activity
GO:0043204 perikaryon
GO:0048471 perinuclear region of cytoplasm
GO:0097055 agmatine biosynthetic process
GO:0098629 trans-Golgi network membrane organization
GO:1902269 positive regulation of polyamine transmembrane transport
GO:1990005 granular vesicle

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm
Cytoplasmic granule
Cytoplasmic vesicle
Endoplasmic reticulum-Golgi intermediate compartment
Golgi apparatus
Membrane
Nucleus
Perikaryon

Domains

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DomainNameCategoryType
IPR000183 Ornithine/DAP/Arg decarboxylaseFamilyFamily
IPR002433 Ornithine decarboxylaseFamilyFamily
IPR009006 Alanine racemase/group IV decarboxylase, C-terminalFamilyHomologous superfamily
IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminalDomainDomain
IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminalDomainDomain
IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding siteSiteBinding site
IPR022657 Orn/DAP/Arg decarboxylase 2, conserved siteSiteConserved site
IPR029066 PLP-binding barrelFamilyHomologous superfamily
IPR031173 Antizyme inhibitor 2FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00114 Pyridoxal phosphateDrugbanksmall molecule
DB00125 ArginineDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
AZIN2_HUMANOAZ3_HUMANBioGRID, IntAct25416956 32296183 details
AZIN2_HUMANPRS8_HUMANBioGRID30545799 details