Entity Details

Primary name PANX1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96RD7
EntryNamePANX1_HUMAN
FullNamePannexin-1
TaxID9606
Evidenceevidence at protein level
Length426
SequenceStatuscomplete
DateCreated2002-01-23
DateModified2021-06-02

Ontological Relatives

GenesPANX1

GO terms

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GOName
GO:0002020 protease binding
GO:0002931 response to ischemia
GO:0005102 signaling receptor binding
GO:0005198 structural molecule activity
GO:0005243 gap junction channel activity
GO:0005262 calcium channel activity
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0005921 gap junction
GO:0006812 cation transport
GO:0006816 calcium ion transport
GO:0007267 cell-cell signaling
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0022829 wide pore channel activity
GO:0022840 leak channel activity
GO:0032059 bleb
GO:0032730 positive regulation of interleukin-1 alpha production
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032991 protein-containing complex
GO:0033198 response to ATP
GO:0044325 transmembrane transporter binding
GO:0048477 oogenesis
GO:0051015 actin filament binding
GO:0097110 scaffold protein binding

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR000990 InnexinFamilyFamily
IPR039099 PannexinFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB01032 ProbenecidDrugbanksmall molecule