Entity Details
| Primary name |
PAR4_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | Q96RI0 |
| EntryName | PAR4_HUMAN |
| FullName | Proteinase-activated receptor 4 |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 385 |
| SequenceStatus | complete |
| DateCreated | 2002-03-27 |
| DateModified | 2021-06-02 |
GO terms
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| GO | Name |
| GO:0004930 | G protein-coupled receptor activity |
| GO:0005576 | extracellular region |
| GO:0005886 | plasma membrane |
| GO:0005887 | integral component of plasma membrane |
| GO:0007165 | signal transduction |
| GO:0007186 | G protein-coupled receptor signaling pathway |
| GO:0007200 | phospholipase C-activating G protein-coupled receptor signaling pathway |
| GO:0007596 | blood coagulation |
| GO:0009611 | response to wounding |
| GO:0015057 | thrombin-activated receptor activity |
| GO:0030168 | platelet activation |
| GO:0035025 | positive regulation of Rho protein signal transduction |
| GO:0051281 | positive regulation of release of sequestered calcium ion into cytosol |
| GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway |
| GO:0060155 | platelet dense granule organization |
Subcellular Location
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| Subcellular Location |
| Cell membrane |
Domains
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| Domain | Name | Category | Type |
| IPR000276 | G protein-coupled receptor, rhodopsin-like | Family | Family |
| IPR003912 | Protease-activated receptor | Family | Family |
| IPR003944 | Protease-activated receptor 4 | Family | Family |
| IPR017452 | GPCR, rhodopsin-like, 7TM | Domain | Domain |
Drugs
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| Drug | Name | Source | Type |
| DB11300 | Thrombin | Drugbank | biotech |
Interactions
2 interactions