Entity Details

Primary name S29A1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99808
EntryNameS29A1_HUMAN
FullNameEquilibrative nucleoside transporter 1
TaxID9606
Evidenceevidence at protein level
Length456
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesSLC29A1

GO terms

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GOName
GO:0001504 neurotransmitter uptake
GO:0005326 neurotransmitter transmembrane transporter activity
GO:0005337 nucleoside transmembrane transporter activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006139 nucleobase-containing compound metabolic process
GO:0006836 neurotransmitter transport
GO:0007595 lactation
GO:0015211 purine nucleoside transmembrane transporter activity
GO:0015213 uridine transmembrane transporter activity
GO:0015858 nucleoside transport
GO:0015860 purine nucleoside transmembrane transport
GO:0015862 uridine transport
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0030431 sleep
GO:0032238 adenosine transport
GO:0060079 excitatory postsynaptic potential
GO:0071333 cellular response to glucose stimulus
GO:0071456 cellular response to hypoxia
GO:0072531 pyrimidine-containing compound transmembrane transport
GO:0098793 presynapse
GO:0098794 postsynapse
GO:0098810 neurotransmitter reuptake
GO:0150104 transport across blood-brain barrier
GO:1901642 nucleoside transmembrane transport

Subcellular Location

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Subcellular Location
Apical cell membrane
Basolateral cell membrane
Cell membrane

Domains

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DomainNameCategoryType
IPR002259 Equilibrative nucleoside transporterFamilyFamily
IPR030195 Equilibrative nucleoside transporter 1FamilyFamily
IPR034764 Nucleoside transporter ENT1/ENT2FamilyFamily
IPR036259 MFS transporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00197 TroglitazoneDrugbanksmall molecule
DB00432 TrifluridineDrugbanksmall molecule
DB00441 GemcitabineDrugbanksmall molecule
DB00544 FluorouracilDrugbanksmall molecule
DB00642 PemetrexedDrugbanksmall molecule
DB00811 RibavirinDrugbanksmall molecule
DB00898 EthanolDrugbanksmall molecule
DB00900 DidanosineDrugbanksmall molecule
DB00943 ZalcitabineDrugbanksmall molecule
DB00987 CytarabineDrugbanksmall molecule
DB01033 MercaptopurineDrugbanksmall molecule
DB01073 FludarabineDrugbanksmall molecule
DB02745 UridineDrugbanksmall molecule
DB09061 CannabidiolDrugbanksmall molecule
DB09327 Tegafur-uracilDrugbanksmall molecule
DB12010 FostamatinibDrugbanksmall molecule
DB14009 Medical CannabisDrugbankbiotech
DB14011 NabiximolsDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
S29A1_HUMANSTK19_HUMANBioGRID, IntAct14667819 details
S29A1_HUMANCREB3_HUMANBioGRID, IntAct, MINT21516116 31515488 details
S29A1_HUMAN5HT2C_HUMANBioGRID, MINT28298427 details