Entity Details

Primary name OVOL2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BRP0
EntryNameOVOL2_HUMAN
FullNameTranscription factor Ovo-like 2
TaxID9606
Evidenceevidence at protein level
Length275
SequenceStatuscomplete
DateCreated2002-09-19
DateModified2021-06-02

Ontological Relatives

GenesOVOL2

GO terms

Show/Hide Table
GOName
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001525 angiogenesis
GO:0001755 neural crest cell migration
GO:0001842 neural fold formation
GO:0001947 heart looping
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0009913 epidermal cell differentiation
GO:0009953 dorsal/ventral pattern formation
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010719 negative regulation of epithelial to mesenchymal transition
GO:0010837 regulation of keratinocyte proliferation
GO:0010944 negative regulation of transcription by competitive promoter binding
GO:0045617 negative regulation of keratinocyte differentiation
GO:0045618 positive regulation of keratinocyte differentiation
GO:0045746 negative regulation of Notch signaling pathway
GO:0046872 metal ion binding
GO:0048557 embryonic digestive tract morphogenesis
GO:0051726 regulation of cell cycle
GO:0060214 endocardium formation
GO:0060347 heart trabecula formation
GO:0060390 regulation of SMAD protein signal transduction
GO:0060716 labyrinthine layer blood vessel development
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000647 negative regulation of stem cell proliferation

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR027756 Ovo-likeFamilyFamily
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
OVOL2_HUMANZN526_HUMANBioGRID, IntAct32296183 details
OVOL2_HUMANPARP1_HUMANBioGRID30542118 details
OVOL2_HUMANHDAC1_HUMANBioGRID30542118 details