Entity Details

Primary name DHRS4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BTZ2
EntryNameDHRS4_HUMAN
FullNameDehydrogenase/reductase SDR family member 4
TaxID9606
Evidenceevidence at protein level
Length278
SequenceStatuscomplete
DateCreated2003-10-10
DateModified2021-06-02

Ontological Relatives

GenesDHRS4

GO terms

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GOName
GO:0000253 3-keto sterol reductase activity
GO:0004090 carbonyl reductase (NADPH) activity
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0005782 peroxisomal matrix
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0006066 alcohol metabolic process
GO:0008104 protein localization
GO:0008202 steroid metabolic process
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0018455 alcohol dehydrogenase [NAD(P)+] activity
GO:0042180 cellular ketone metabolic process
GO:0042802 identical protein binding
GO:2000379 positive regulation of reactive oxygen species metabolic process

Subcellular Location

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Subcellular Location
Nucleus
Peroxisome

Domains

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DomainNameCategoryType
IPR002347 Short-chain dehydrogenase/reductase SDRFamilyFamily
IPR020904 Short-chain dehydrogenase/reductase, conserved siteSiteConserved site
IPR029511 Dehydrogenase/reductase SDR member 4-likeFamilyFamily
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00162 Vitamin ADrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
DHRS4_HUMANPEX5_HUMANBioGRID20178365 22002062 30378028 details
DHRS4_HUMANRICTR_HUMANBioGRID17461779 details