Entity Details

Primary name KMO_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15229
EntryNameKMO_HUMAN
FullNameKynurenine 3-monooxygenase
TaxID9606
Evidenceevidence at protein level
Length486
SequenceStatuscomplete
DateCreated2006-04-04
DateModified2021-06-02

Ontological Relatives

GenesKMO

GO terms

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GOName
GO:0004502 kynurenine 3-monooxygenase activity
GO:0005615 extracellular space
GO:0005741 mitochondrial outer membrane
GO:0005829 cytosol
GO:0006569 tryptophan catabolic process
GO:0007568 aging
GO:0009651 response to salt stress
GO:0016021 integral component of membrane
GO:0016174 NAD(P)H oxidase H2O2-forming activity
GO:0019674 NAD metabolic process
GO:0019805 quinolinate biosynthetic process
GO:0034276 kynurenic acid biosynthetic process
GO:0034354 'de novo' NAD biosynthetic process from tryptophan
GO:0043420 anthranilate metabolic process
GO:0050660 flavin adenine dinucleotide binding
GO:0070189 kynurenine metabolic process
GO:0071222 cellular response to lipopolysaccharide
GO:0071347 cellular response to interleukin-1
GO:0071949 FAD binding
GO:0097052 L-kynurenine metabolic process
GO:1901216 positive regulation of neuron death
GO:1903296 positive regulation of glutamate secretion, neurotransmission

Subcellular Location

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Subcellular Location
Mitochondrion outer membrane

Domains

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DomainNameCategoryType
IPR002938 FAD-binding domainDomainDomain
IPR027545 Kynurenine 3-monooxygenaseFamilyFamily
IPR036188 FAD/NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
KMO_HUMANHD_HUMANIntAct32814053 details
KMO_HUMANFBX7_HUMANBioGRID27503909 details