Entity Details

Primary name RTN4R_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BZR6
EntryNameRTN4R_HUMAN
FullNameReticulon-4 receptor
TaxID9606
Evidenceevidence at protein level
Length473
SequenceStatuscomplete
DateCreated2002-11-25
DateModified2021-06-02

Ontological Relatives

GenesRTN4R

GO terms

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GOName
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007166 cell surface receptor signaling pathway
GO:0008201 heparin binding
GO:0009986 cell surface
GO:0010977 negative regulation of neuron projection development
GO:0022038 corpus callosum development
GO:0023041 neuronal signal transduction
GO:0030517 negative regulation of axon extension
GO:0031362 anchored component of external side of plasma membrane
GO:0035025 positive regulation of Rho protein signal transduction
GO:0035374 chondroitin sulfate binding
GO:0038023 signaling receptor activity
GO:0038131 neuregulin receptor activity
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043198 dendritic shaft
GO:0043204 perikaryon
GO:0043547 positive regulation of GTPase activity
GO:0044295 axonal growth cone
GO:0045121 membrane raft
GO:0048681 negative regulation of axon regeneration
GO:0050771 negative regulation of axonogenesis
GO:0070062 extracellular exosome
GO:1905573 ganglioside GM1 binding
GO:1905576 ganglioside GT1b binding

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Membrane raft
Perikaryon

Domains

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DomainNameCategoryType
IPR000483 Cysteine-rich flanking region, C-terminalDomainDomain
IPR001611 Leucine-rich repeatRepeatRepeat
IPR003591 Leucine-rich repeat, typical subtypeRepeatRepeat
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily

Diseases

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